Anti-Influenza A virus PB2 protein antibody GTX125926 from GeneTex

Product Specs
ItemAnti-Influenza A virus PB2 protein antibody
CompanyGeneTex
Price Pricing Info Supplier Page
Catalog NumberGTX125926
ApplicationsWB, ICC/IF, IP
ReactivityInfluenza A virus, Influenza A virus ( H1N1)
ClonalityPolyclonal
HostRabbit
Quantity25 µl
Concentration1.27mg/ml
Conjugate/TagUnconjugated
IsotypeIgG
Antibody TypePrimary Antibodies
ImmunogenRecombinant protein encompassing a sequence within the C-terminus region of Influenza A virus PB2 (A/Puerto Rico/8/1934(H1N1)). The exact sequence is proprietary
FormatPBS, 20% Glycerol, 0.025% ProClin 300
PurityPurified by antigen-affinity chromatography
TargetInfluenza A virus PB2 protein
Research AreaInfectious Diseases
Molecular Weight86
NCBI Gene AliasesInfluenza A Virus Polymerase basic protein 2, Influenza A Virus PB2

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

(1) An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerizationNature CommunicationsOctober 10, 2023Carol M. Sheppard, Daniel H. Goldhill, Olivia C. Swann, Ecco Staller, Rebecca Penn, Olivia K. Platt, Ksenia Sukhova, Laury Baillon, Rebecca Frise, Thomas P. Peacock, et al.α-vinculin (Abcam ab129002, 1:2000), mouse α-tubulin (Abcam ab7291, 1:2500), rabbit α-IAV PB2 (GeneTex GTX125926, 1:2000), rabbit α-IAV PB1 (GeneTex GTX125923, 1:500), rabbit α-IAV PA (GeneTex GTX118991 1:500) mouse

(2) The SUMO-interacting motif in NS2 promotes adaptation of avian influenza virus to mammalsScience advancesJuly 14, 2023Sun L, Kong H, Yu M, Zhang Z, Zhang H, Na L, Qu Y, Zhang Y, Chen H, Wang X.rabbit anti-Flag (1:5000 for WB; Sigma-Aldrich, F7425), rabbit anti-IAV PB2 (1:5000 for WB; GeneTex, GTX125926), mouse anti-human ANP32A(1:5000 for WB; Proteintech, 67687-1-Ig), rabbit anti-human ANP32B (1:5000

(3) The synergistic effect of residues 32T and 550L in the PA protein of H5 subtype avian influenza virus contributes to viral pathogenicity in micePLOS PathogensJuly 3, 2023Hui Yang, Yurui Dong, Ying Bian, Chenzhi Huo, Chuncheng Zhu, Tao Qin, Sujuan Chen, Daxin Peng, Xiufan Liurabbit anti-PA pAb (GTX125932, 1:1000), rabbit anti-PB1 pAb (GTX125923, 1:1000) and rabbit anti-PB2 pAb (GTX125926, 1:1000) were purchased from GeneTex. Rabbit anti-STAT1 mAb (14995S, 1:1000), rabbit anti-pSTAT1 mAb

(4) Mammalian ANP32A and ANP32B Proteins Drive Differential Polymerase Adaptations in Avian Influenza VirusJournal of virologyMay 31, 2023Peacock TP, Sheppard CM, Lister MG, Staller E, Frise R, Swann OC, Goldhill DH, Long JS, Barclay WS.were detected with mouse α-FLAG (F1804, Sigma), rabbit α-Vinculin (AB129002, Abcam), rabbit α-PB2 (GTX125926, GeneTex), and mouse α-NP ([C43] AB128193, Abcam). The following near-infrared (NIR) fluorescently tagged

(5) Avian Influenza A Virus Polymerase Can Utilize Human ANP32 Proteins To Support cRNA but Not vRNA SynthesismBioFebruary 28, 2023Swann OC, Rasmussen AB, Peacock TP, Sheppard CM, Barclay WS.PBS with 2% bovine serum albumin and 0.1% Tween for 30 min, incubated in rabbit α-PB2 (catalog no. GTX125926; Genetex) antibody for 1 h at room temperature, followed by goat α-rabbit AF647 (Invitrogen) plus DAPI

(6) The ubiquitination landscape of the influenza A virus polymeraseNature communicationsFebruary 11, 2023Günl F, Krischuns T, Schreiber JA, Henschel L, Wahrenburg M, Drexler HCA, Leidel SA, Cojocaru V, Seebohm G, Mellmann A, et al.in blocking buffer). Polymerase subunits were detected using the primary antibodies rabbit anti-PB2 (GTX125926, Genetex; 1:1000 in blocking buffer), rabbit anti-PB1 (GTX125923, Genetex; 1:2000 in blocking buffer),

(7) Nonmuscle myosin IIA promotes the internalization of influenza A virus and regulates viral polymerase activity through interacting with nucleoprotein in human pulmonary cellsVirologica SinicaFebruary 1, 2023Chen J, Liu J, Chen Z, Feng D, Zhu C, Fan J, Zhang S, Zhang X, Xu J.virus PB1 antibody (1:2,000, GTX125923, GeneTex), rabbit anti-Influenza A virus PB2 antibody (1:2,000, GTX125926, GeneTex), goat anti-rabbit IgG-HRP (1:5,000, B2615, Santa Cruz Biotechnology), and goat anti-mouse IgG-HRP

(8) Influenza A virus strain PR/8/34, but neither HAM/2009 nor WSN/33, is transiently inhibited by the PB2-targeting drug paliperidoneArchives of virologyJanuary 13, 2023Panagiotidis GD, Müller C, Binder M, Weber F.monoclonal anti-p53 antibody (Calbiochem, OP43) and rabbit anti-NP (Genetex GTX125989) and anti-PB2 (Genetex GTX125926) polyclonal antibodies as described [10]. Subsequently, the immunoprecipitates were probed with mouse

(9) Nisoldipine Inhibits Influenza A Virus Infection by Interfering with Virus Internalization ProcessVirusesDecember 8, 2022Huang Y, Li Y, Chen Z, Chen L, Liang J, Zhang C, Zhang Z, Yang J.(Shanghai, China). The following antibodies were used: influenza A virus PB2 protein antibody (Genetex, GTX125926); influenza A virus NP antibody (Genetex, GTX125989); mouse anti-transferrin antibody (Bioss, bsm-33244M);

(10) SRSF5-Mediated Alternative Splicing of M Gene is Essential for Influenza A Virus Replication: A Host-Directed Target Against Influenza VirusAdvanced science (Weinheim, Baden-Wurttemberg, Germany)December 1, 2022Li Q, Jiang Z, Ren S, Guo H, Song Z, Chen S, Gao X, Meng F, Zhu J, Liu L, et al.GTX125928), M2 (GeneTex, GTX125951), PA (GeneTex, GTX118991), PB1 (GeneTex, GTX125923), PB2 (GeneTex, GTX125926), NP (GeneTex, GTX125989), control rabbit IgG polyclonal (ABclonal Biotechnology, AC005), Fluor 488‐goat

(11) The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signallingNature communicationsOctober 21, 2022Yang H, Dong Y, Bian Y, Xu N, Wu Y, Yang F, Du Y, Qin T, Chen S, Peng D, et al.purchased from the indicated manufacturers. Mouse anti-NP mAb (GTX629633, 1:1000) and rabbit anti-PB2 pAb (GTX125926, 1:1000) were purchased from GeneTex. Rabbit anti-STAT1 mAb (14995S, 1:1000), rabbit anti-pSTAT1 mAb

(12) Transient RNA structures cause aberrant influenza virus replication and innate immune activationScience advancesSeptember 9, 2022French H, Pitré E, Oade MS, Elshina E, Bisht K, King A, Bauer DLV, Te Velthuis AJW.proteins were detected using rabbit polyclonal antibodies anti-PB1 (GTX125923, GeneTex), anti-PB2 (GTX125926, GeneTex), and anti-NP (GTX125989, GeneTex) diluted 1:1000 in TBSTM [tris-buffered saline (TBS)/0.1%

(13) G Protein Subunit β1 Facilitates Influenza A Virus Replication by Promoting the Nuclear Import of PB2Journal of virologyJune 22, 2022Zheng H, Ma L, Gui R, Lin X, Ke X, Jian X, Ye C, Chen Q.

(14) PIAS1-mediated SUMOylation of influenza A virus PB2 restricts viral replication and virulencePLoS pathogensApril 1, 2022Wang G, Zhao Y, Zhou Y, Jiang L, Liang L, Kong F, Yan Y, Wang X, Wang Y, Wen X, et al.anti-M1 pAb (GTX125928, GeneTex), rabbit anti-M2 pAb (GTX125951, GeneTex), and rabbit anti-PB2 pAb (GTX125926, GeneTex). The mouse anti-PB2 mAb, mouse anti-PB1 mAb, rabbit anti-PB1 pAb, mouse anti-PA mAb, rabbit

(15) p21 restricts influenza A virus by perturbing the viral polymerase complex and upregulating type I interferon signalingPLoS pathogensFebruary 1, 2022Ma C, Li Y, Zong Y, Velkov T, Wang C, Yang X, Zhang M, Jiang Z, Sun H, Tong Q, et al.purchased from GenScript (Nanjing, China); and anti-PA (GTX118991), anti-PB1 (GTX125923) and anti-PB2 (GTX125926) antibodies were purchased from GeneTex (Irvine, CA, USA). The secondary antibodies used in western blotting

(16) eIF5A is activated by virus infection or dsRNA and facilitates virus replication through modulation of interferon productionFrontiers in cellular and infection microbiologyJanuary 1, 2022Seoane R, Llamas-González YY, Vidal S, El Motiam A, Bouzaher YH, Fonseca D, Farrás R, García-Sastre A, González-Santamaría J, Rivas C.

(17) Evidence that two instead of one defective interfering RNA in influenza A virus-derived defective interfering particles (DIPs) does not enhance antiviral activityScientific reportsOctober 14, 2021Bdeir N, Arora P, Gärtner S, Pöhlmann S, Winkler M.

(18) In Vivo Therapy with M2e-Specific IgG Selects for an Influenza A Virus Mutant with Delayed Matrix Protein 2 ExpressionmBioAugust 31, 2021Van den Hoecke S, Ballegeer M, Vrancken B, Deng L, Job ER, Roose K, Schepens B, Van Hoecke L, Lemey P, Saelens X.rabbit, 1/1,000, catalog no. GTX125932; GeneTex), and PB2 (polyclonal rabbit, 1/1,000, catalog no. GTX125926; GeneTex), or GAPDH (polyclonal rabbit, 1/2,500, catalog no. ab9485; Abcam). For the detection, the

(19) 3-Indoleacetonitrile Is Highly Effective in Treating Influenza A Virus Infection In Vitro and In VivoVirusesJuly 23, 2021Zhao X, Zhao L, Zhao Y, Huang K, Gong W, Yang Y, Zhao L, Xia X, Li Z, Sheng F, et al.

(20) MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomesNature communicationsJuly 20, 2021Liu X, Xu F, Ren L, Zhao F, Huang Y, Wei L, Wang Y, Wang C, Fan Z, Mei S, et al.(GeneTex, Cat#629696, 1:2000; Cat# GTX125990, 1:2000; Cat# GTX125932, 1:2000; Cat# GTX125923, 1:2000; Cat# GTX125926, 1:2000, respectively), HA.11 Epitope Tag (BioLegend, Cat# 901501 or Cat# 902301; 1:1000), and actin

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Anti-Influenza A virus PB2 protein antibody

Anti-Influenza A virus PB2 protein antibody

Anti-Influenza A virus PB2 protein antibody from GeneTex

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Anti-Influenza A virus PB2 protein antibody from GeneTex

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